Follica's pivotal study and FDA filing in 2020

Discuss the latest news about cutting edge hair loss research: Tsuji, RepliCel, Follicum, etc.
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blackg
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Re: Follica's pivotal study and FDA filing in 2020

Post by blackg » 1 week ago

That Guy wrote:
2 weeks ago
Sure thing, bro — it's done.
You dissapoint me sometimes.
Oh Canada, save us all.

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That Guy
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Re: Follica's pivotal study and FDA filing in 2020

Post by That Guy » 1 week ago

blackg wrote:
1 week ago
You dissapoint me sometimes.
Not as much as you disappoint me.

Anyway, some of the most-relevant details from Follica's studies so far.

• The first studies were just on wounding, no drugs applied. Still worked.
• The theory that the results are not sustainable without at least some hair-growth-promoting agent is now confirmed. You'll have to keep using whatever compounds or presumably at least finasteride to keep the results. The theory has been around for a long time that the results may not be sustainable without drugs because the hair's neo-genesis takes place from the same skin (cells) as the originals.
• Each study so far has only done one pass of the treatment. So for most people, a couple or three visits should be able to fill in bald areas.
• They also tried a lithium-gel and later minoxidil.
• The device only goes about as deep as the first layer of skin. It has to do with this "quorum-sensing" thing. As long thought, there does appear to be an ideal depth and area that must be covered for optimal results. Too deep, too narrow, etc. makes the difference between hair growth and nothing. The approach they seem to be taking is "lots of needles, shallow depth". This could speak favorably to a future development involving nano-needling.

All in all I'm very stoked about this and will definitely be getting it done when its out in the next couple years. Much better option than a transplant.

Hanginginthewire
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Re: Follica's pivotal study and FDA filing in 2020

Post by Hanginginthewire » 1 week ago

That Guy, fresh from binge-watching Red Ice Tv. Can you take your own advice and find a hobby besides spamming hair loss forums with off topic political bullshit?

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That Guy
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Re: Follica's pivotal study and FDA filing in 2020

Post by That Guy » 1 week ago

Hanginginthewire wrote:
1 week ago
That Guy, fresh from binge-watching Red Ice Tv. Can you take your own advice and find a hobby besides spamming hair loss forums with off topic political bullshit?
You haven't noticed, because you're too obsessed with trying to one-up me to notice, but I'm presently the only one in this thread posting on-topic.

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rclark
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Regimen: Dustasteride 0.5 milligrams daily, Finasteride 1mg topical, Progesterone 2% (22mg daily), Minoxidil 15% hair growth only).
Using 1.5 mm needle on all bald/balding areas weekly.

Re: Follica's pivotal study and FDA filing in 2020

Post by rclark » 1 week ago

Did Follica ever test their tool on men past forty?
Think happy thoughts.

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That Guy
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Re: Follica's pivotal study and FDA filing in 2020

Post by That Guy » 1 week ago

rclark wrote:
1 week ago
Did Follica ever test their tool on men past forty?
Yes, it was tested on men age 35 - 45

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blackg
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Re: Follica's pivotal study and FDA filing in 2020

Post by blackg » 1 week ago

That Guy wrote:
1 week ago
Yes, it was tested on men age 35 - 45
Change or self destruct.
Oh Canada, save us all.

pjhair
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Re: Follica's pivotal study and FDA filing in 2020

Post by pjhair » 1 week ago

blackg wrote:
1 week ago
Change or self destruct.
You are funny blackg :lol: :lol:
Trump 2020

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DerPapillus
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Re: Follica's pivotal study and FDA filing in 2020

Post by DerPapillus » 1 week ago

That Guy wrote:
1 week ago
Not as much as you disappoint me.

Anyway, some of the most-relevant details from Follica's studies so far.

• The first studies were just on wounding, no drugs applied. Still worked.
• The theory that the results are not sustainable without at least some hair-growth-promoting agent is now confirmed. You'll have to keep using whatever compounds or presumably at least finasteride to keep the results. The theory has been around for a long time that the results may not be sustainable without drugs because the hair's neo-genesis takes place from the same skin (cells) as the originals.
• Each study so far has only done one pass of the treatment. So for most people, a couple or three visits should be able to fill in bald areas.
• They also tried a lithium-gel and later minoxidil.
• The device only goes about as deep as the first layer of skin. It has to do with this "quorum-sensing" thing. As long thought, there does appear to be an ideal depth and area that must be covered for optimal results. Too deep, too narrow, etc. makes the difference between hair growth and nothing. The approach they seem to be taking is "lots of needles, shallow depth". This could speak favorably to a future development involving nano-needling.

All in all I'm very stoked about this and will definitely be getting it done when its out in the next couple years. Much better option than a transplant.
Hi,

You mention that the results are not sustainable because the hair's neo-genesis takes place from the same skin cells as the former miniaturized hairs, something that I kind of suspected myself and anticipated even as early as after the famous BaldTruthTalk interview with one of the leading research figures in the field (thanks to the famous Desmond84) when said person kind of alluded to this. But:
What are your thought on the possibility of promoting neo-genesis of follicles in the safe-zones (donor of transplants) after transplant surgery, and then opt for another transplant...in practice a drastic increase in donor hairs?
In fact, a couple of years back even Follica themselves alluded to this possibility through some PP-slides which I believe another legendary user great in researching relevant and new cutting edge news made public on hairlosstalk (forgive on not remembering his name)...
Just curious...how do you view this (realistic) and your stance on it in general (would you use it)....

Cheers
''I have hope for life man'' - buckthorn, 2018

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That Guy
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Re: Follica's pivotal study and FDA filing in 2020

Post by That Guy » 1 week ago

DerPapillus wrote:
1 week ago
Hi,

You mention that the results are not sustainable because the hair's neo-genesis takes place from the same skin cells as the former miniaturized hairs, something that I kind of suspected myself and anticipated even as early as after the famous BaldTruthTalk interview with one of the leading research figures in the field (thanks to the famous Desmond84) when said person kind of alluded to this. But:
What are your thought on the possibility of promoting neo-genesis of follicles in the safe-zones (donor of transplants) after transplant surgery, and then opt for another transplant...in practice a drastic increase in donor hairs?
In fact, a couple of years back even Follica themselves alluded to this possibility through some PP-slides which I believe another legendary user great in researching relevant and new cutting edge news made public on hairlosstalk (forgive on not remembering his name)...
Just curious...how do you view this (realistic) and your stance on it in general (would you use it)....

Cheers
I think it's a pretty-lofty stretch goal, to be honest. That may not even be possible. There's a lot of potential variables involving scar tissue, the healing of said scar tissue with Follica, long-term effects of repeatedly cutting chunks out of you, and all kinds of other things that I'm unaware of being seriously studied (yet) that are reasonable to assume could pose obstacles to its feasibility.

If it is possible to do that, it could very well be something you might not want to do more than once.

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